Mouse Processed Pseudogenes (Apexp1 and Cbx3p1) for Apex Nuclease and Chromobox Homolog 3

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Title
Mouse Processed Pseudogenes (Apexp1 and Cbx3p1) for Apex Nuclease and Chromobox Homolog 3
Author
著者 関 周司
著者(別表記) Seki Shuji
著者 真鍋 芳江
著者(別表記) Manabe Yoshie
著者 Nakamura Takashi
著者(別表記) Nakamura Takashi
著者 Yao Ming
著者(別表記) Yao Ming
著者 関 雄一
著者(別表記) Seki Yuichi
Abstract

Mouse processed pseudogenes for Apex nuclease and chromobox homolog 3 were isolated from a mouse genomic library. Inserts of the three isolated clones (clones 2, 6 and 16) were sequenced and analyzed. Clones 2 and 6 were overlapping clones, and the inserts covered a 14.9 kilobase (kb) genomic fragment. The fragment contains a processed Apex pseudogene (designated as mouse Apexpl) and a processed Cbx3 pseudogene (designated as mouse Cbx3pl). These pseudogenes are located in inactive LINE (long interspersed repetitive element) sequences. Calculation of nucleotide substitution rates suggests that the non-functional mouse Apexpl arose 24 million years ago, and that the non-functional mouse Cbx3pl arose even earlier, 56 million years ago. The insert sequence of the clone 16 contains a processed Apex pseudogene (designated as mouse Apexp2) differing from the Apexpl.

Subject
460 Biology
Keyword
Pseudogenes
Apexp1
Cbx3p1
Publish Date
2002
Publication Title
Chugokugakuen journal
Volume
1
Start Page
13
End Page
17
ISSN
1348-1452
NCID
AA11806612
Publisher
中国学園大学/中国短期大学
Copyright Holders
中国学園大学/中国短期大学
Official URL
Contents Type
Departmental Bulletin Paper
language
English
File Version
publisher